Welcome To Drug Analysis & Research Laboratory
Overview:
Ø Creation of scientific knowledge through research work.
Ø Providing quality knowledge, research and services to the society of the country.
Ø Developing comprehensive and appropriate technology approaches to drug analysis and research.
Ø Enhancing capacity building of the centre through installation and operation of standard scientific instruments and equipment along with personnel skill development for the analysis and research.
Ø Generation
of highly skilled scientific and technical manpower.
Research Area:
ØDrug Analysis and Research Laboratory is conducting and supporting basic and clinical research on drug i.e. new drug development, isolation, synthesis, drug interaction, its consequences in vitro and in vivo, analytical method development of drugs and validation, bioavailability and bioequivalence studies in animal and human models.
It also
creates demands for research and analysis. These demands directly and
indirectly are influenced by the interactions, program directions, and
priorities of scientists, faculties and graduate students and their
relationships to their academic departments.
Services:
Besides
conducting research, Drug Analysis and Research Laboratory also provides analytical services to faculty members of the University of Dhaka as well as to
individuals, other institutions, companies, agency of outside of the university.
Facilities:
Drug Analysis and Research Laboratory has the following facilities for conducting research and analysis.
|
Name of the instrument |
Model |
Manufacturer |
| HPLC (UV and Fluorescence detectors, Autoinjector) | Prominence,
LC 20AD | Shimadzu, Japan |
|
ELISA Reader |
LisaScan EM |
Erba, Germany |
|
Hot Plate Magnetic Stirrer |
RSM-04H |
Phoenix Instrument, Germany |
|
Distilled water plant |
LWDB-400M |
Laboid, India |
|
Fume hood |
22/Eco Flux V120 |
Folabo, Italy |
|
Turbo Evaporator |
AT-EV-50 |
Athena tech, India |
|
UV lamp (254 nm, 356 nm) |
ENF-280C/FE |
Spectroline, USA |
|
Soxhlet Extractor |
98-I-B |
China |
|
Vortex mixer |
|
|
|
Ultrasonic bath |
Ultrasons-Medi -II |
J.P. Selecta, Spain |
|
Centrifuge machine (Max 4500 rpm) |
Z 36 HK |
HermleLabortechnik GmbH, Germany |
|
Oven (up to 250 oC) |
UNE 600 |
Memmert GmbH, Germany |
|
Hardness tester |
HDT-300F |
Logan Instrument Corporation, USA |
|
Digital Melting point apparatus |
WRS-1B |
Sunonwealth Electric Machine Industry Co. Ltd., Taiwan |
|
Friability Tester |
FAB-2S |
Logan Instruments Corporation, USA |
|
Digital Analytical Balance |
AS220.R2 |
Radwag, Poland |
|
Tap Density Tester |
TAP-2S |
Logan Instruments Corporation, USA |
|
Thermostatic water bath (Quantity 3) |
Unitronic OR |
J. P. Selecta, Spain |
|
Fluorescence spectrophotometer |
F 7000 |
Hitachi, Japan |
|
Flame photometer |
PFP7 |
Jenway, UK |
|
pH meter |
Orion Star A111 |
Thermo Scientific, USA |
|
Colony counter |
SC-6 |
Stuart, UK |
|
Viscometer (Quantity 2) |
LVDVE |
Brookfield, USA |
|
Conductivity meter |
CD-2005 |
J. P. Selecta, Spain |
|
Rotavapor |
R-215 |
Buchi, Switzerland |
|
Digital rough balance (30 kg) |
Series No. 220 |
China |
|
Dissolution tester |
UDT-804 |
Logan Instruments Corporation, USA |
|
Tablet disintegration tester |
DST-3 |
Logan Instruments Corporation, USA |
|
UV-Spectrophotometer (Assembling with Dissolution tester) |
UV-1800 |
Shimadzu, Japan |
|
Total Organic Carbon Analyzer (TOC) |
TOC-V CPH |
Shimadzu, Japan |
|
Ion Exchange Analyzer |
|
Metrohm,
Switzerland |
''
Personnel:
Lab In charge: Dr. Md. Zakir Sultan, Principal Scientist
Lab Attendant (Senior Grade): Konik Kumar Sarkar
Publications:
| Sl. | Article | Type | Year | Link |
|---|---|---|---|---|
| 1 | Adeeba Anjum, Md. Zakir Sultan, Mohammad Abdullah Al Mansur, Choudhuri M. Hasan and Mohammad A. Rashid. Assessment of antioxidant, antimicrobial, cytotoxicity and thrombolytic potential of Erythrina fusca Lour grown in Bangladesh. Bangladesh Pharmaceutical Journal 25(1):1-8, 2022. | Journal | 2022 | Link |
| 2 | Fahima Aktar, Md. Jamal Hossain, Md. Zakir Sultan and Mohammad A. Rashid. Iron (II) and Zinc (II) complexes of gemifloxacin mesylate: synthesis, characterization, serum binding profiling, and evaluation of antimicrobial activity. Journal of Bangladesh Academy of Sciences. 46(2); 203-211: December 2022. | Journal | 2022 | Link |
| 3 | Dey S., Md. Zakir Sultan and Salam MA. Synthesis, characterization of ceftibuten-copper (ii) complex and prediction of its biological activity. Asian Journal of Chemistry 33(1): 190-194 (2021). | Journal | 2021 | Link |
| 4 | Hossain MJ, Kuddus MR, Rashid MA and Md. Zakir Sultan. Understanding and dealing the SARS-CoV-2 infection: An updated concise review. Bangladesh Pharmaceutical Journal 24(1): 61-75; 2021 | Journal | 2021 | Link |
| 5 | Aktar F, Md. Zakir Sultan and Rashid MA. Chromium (III) complexes of metformin, dapagliflozin, vildagliptin and glimepiride potentiate antidiabetic activity in animal model. International Journal of Current Research and Review 13(05): 64-69; 2021. | Journal | 2021 | Link |
| 6 | Hossain I, Soliman MM, El-Naggar ME, Md. Zakir Sultan, Kechi A, Abdel Salam NR,Abu-Saied MA, Chowdhury M. Synthesis and characterization of graphene oxide–ammonium ferricsulfate composite for the removal of dyes from tannery wastewater, Journal of Materials Research and Technology, 12:1715-1727; 2021. | Journal | 2021 | Link |
| 7 | Hossain MJ, Md. Zakir Sultan, Rashid MA, Kuddus MR. Interactions of linagliptin, rabeprazole sodium, and their formed complex with bovine serum albumin: computational docking and fluorescence spectroscopic methods. Analytical Science Advances, 2:480–494; 2021. | Journal | 2021 | Link |
| 8 | Anjum A, Sultan MZ, Ferdosh S, Islam MK, Rashid MA, Nahar L, Sarker SD. Flavonoid, pterocarpans and steroid from Erythrina fusca Lour. growing in Bangladesh: isolation, and antimicrobial and free-radical scavenging activity. Journal of Medicinal Plants 2021; 20(79): 37-46. | Journal | 2021 | Link |
| 9 | Shuchismita Dey, Md. Zakir Sultan and Md. Abdus Salam. Nickel(II)-complex of ceftibuten dihydrate: synthesis, characterization and thermal study. The Dhaka University Journal of Pharmaceutical Sciences. 2021; 20(2): 219-225. | Journal | 2021 | Link |
| 10 | Adeeba Anjum, Md. Ruhul Kuddus, Md. Zakir Sultan, Abdullah Al Mansur, Choudhury M. Hasan and Mohammad A. Rashid. Phytochemical and biological investigation of Bridelia tomentosa Blume growing in Bangladesh. The Dhaka University Journal of Pharmaceutical Sciences. 2021; 20(2): 213-218. | Journal | 2021 | Link |
| 11 | M.J. Hossain, Md. Zakir Sultan, M.A. Rashidand M.R. Kuddus. In vitro interactions of secnidazole and its iron (ii), copper (ii) complexes with bovine serum albumin by fluorescencequenching method. Bangladesh Pharmaceutical Journal 23(1): 1-9, 2020. | Journal | 2020 | |
| 12 | Hossain M.I., Deb A.K., Md. Zakir Sultan, Shaikh A.A., Chowdhury M., Sarker M.R. Synthesis and application of graphene oxide (GO) for removal of cationic dyes from tannery effluents. Textile & Leather Review 3(3):146-157, 2020. | Journal | 2020 | Link |
| 13 | Hossain MJ, Md. Zakir Sultan, Rashid MA, Kuddus MR. Does rabeprazole sodium alleviate the anti-diabetic activity oflinagliptin? Drug-drug interaction analysis by in vitro and in vivo methods. Drug Research 70(11): 519-527, 2020. | Journal | 2020 | Link |
| 14 | Hossain MJ, Rashid MA, Md. Zakir Sultan. Transition metal chelation augments the half-life of secnidazole: molecular docking and fluorescence spectroscopic approaches. Drug Research 70(12): 583-592, 2020. | Journal | 2020 | Link |
| 15 | Aktar F, Md. Zakir Sultan and Rashid MA. Study of the effects of complexation of lead with metformin, glimepiride, vildagliptin and dapagliflozin in mice model. Microbial Bioactives 3(1): E125-E133 (2020). | Journal | 2020 | Link |
| 16 | Z. Sultana, R. Sultana, M. Rokonujjaman, H.A. Simol, Md. Zakir Sultan and M.A. Salam. Impact of gypsum and potash fertilizers on heavy metals and nutrients levels in some selected leafy vegetables and assessment of potential health risk. Bangladesh Pharmaceutical Journal 22(1): 56-67, 2019. | Journal | 2019 | |
| 17 | R. Sultana and Md. Zakir Sultan. Complexation of andrographolide, mirabegron and suvorexant and bioactivity study of the complexes. Microbial Bioactives, 2019, 2, 76-81. https://doi.org/10.25163/microbbioacts.21010A0410130219 | Journal | 2019 | |
| 18 | R. Begum, Md. Zakir Sultan, J.A. Chowdhuryand M.S. Amran. In vitro pharmaceutical equivalence study of three brandsof atenolol tablets available in Bangladesh. Dhaka University Journal of Pharmaceutical Sciences, 18(1): 43-48, 2019 (June). DOI: https://doi.org/10.3329/dujps.v18i1.41426 | Journal | 2019 | |
| 19 | A. Rahman, M.R. Haque, Md. Zakir Sultan,M.M. Rahman and Mohammad A. Rashid. Enantiomeric determination of carvedilol by a newlydeveloped and validated chiral HPLC method. Dhaka University Journal of Pharmaceutical Sciences, 18(1): 61-68, 2019 (June)DOI: https://doi.org/10.3329/dujps.v18i1.41432 | Journal | 2019 | |
| 20 | F. Tahia, Md. Zakir Sultan, M.K. Islam and M. A. Rashid. Thermochemical properties and bioactivity of the metallic complexes of levofloxacin. Asian Journal of Organic & Medicinal Chemistry 4(2): 89-93, 2019. | Journal | 2019 | |
| 21 | F. Aktar, Md. Zakir Sultan and M.A. Rashid. In vitro complexation of olmesartanmedoxomil withdapagliflozin, vildagliptin and metformin. Dhaka University Journal of Pharmaceutical Sciences, 18(2): 271-280, 2019. | Journal | 2019 | |
| 22 | F. Yasmin, R. Sultana and Md. Zakir Sultan. Assessment of heavy metals and thermal properties of soil-rice-husk system collected from three districts of Bangladesh. Dhaka University Journal of Biological Sciences 27(2): 163-173, 2018. | Journal | 2018 | |
| 23 | R. Sultana and Md. Zakir Sultan. In vitro effect of Withania somnifera, Mucuna pruriens and Pausinystalia johimbe on hepatic cytochrome P450 in rat. Bangladesh Pharmaceutical Journal 21(2): 118-122, 2018. | Journal | 2018 |